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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TUBB All Species: 44.85
Human Site: S339 Identified Species: 98.67
UniProt: P07437 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P07437 NP_821133.1 444 49671 S339 N V Q N K N S S Y F V E W I P
Chimpanzee Pan troglodytes Q8WP14 444 49773 S339 N I Q D K N S S Y F A D W L P
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9ERD7 450 50400 S339 A I Q S K N S S Y F V E W I P
Rat Rattus norvegicus Q6P9T8 445 49782 S339 N V Q N K N S S Y F V E W I P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus P09244 444 49652 S339 N V Q N K N S S Y F V E W I P
Frog Xenopus laevis Q91575 444 49709 S339 N V Q N K N S S Y F V E W I P
Zebra Danio Brachydanio rerio NP_942113 444 49654 S339 N V Q N K N S S Y F V E W I P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q24560 447 50129 S339 N I Q N K N S S Y F V E W I P
Honey Bee Apis mellifera XP_392313 447 50157 S339 N I Q N K N S S Y F V E W I P
Nematode Worm Caenorhab. elegans P41937 444 49782 S339 N V Q N K N S S Y F V E W I P
Sea Urchin Strong. purpuratus XP_791790 447 50098 S339 N V Q N K N S S Y F V E W I P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.9 N.A. N.A. N.A. 91.3 97.3 N.A. N.A. 100 99.7 98.6 N.A. 94.4 94.6 93 96.2
Protein Similarity: 100 95.2 N.A. N.A. N.A. 95.1 98.8 N.A. N.A. 100 99.7 99.5 N.A. 97.7 98.2 97.5 98.4
P-Site Identity: 100 66.6 N.A. N.A. N.A. 80 100 N.A. N.A. 100 100 100 N.A. 93.3 93.3 100 100
P-Site Similarity: 100 93.3 N.A. N.A. N.A. 93.3 100 N.A. N.A. 100 100 100 N.A. 100 100 100 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 91 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 37 0 0 0 0 0 0 0 0 0 0 0 91 0 % I
% Lys: 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 91 0 0 82 0 100 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 % P
% Gln: 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 10 0 0 100 100 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 64 0 0 0 0 0 0 0 0 91 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _